
Lithium Restores Brain Function and Behavior in Autism Autism Featured Genetics Neuroscience December 27, 2024 Summary : Lithium , a drug widely used for bipolar disorder , may also treat autism spectrum disorder ASD according to new research . The study found that lithium restored brain function and reduced behavioral symptoms in mice with Dyrk1a gene mutations , a known ASD risk . factor Administered during the juvenile period , lithium normalized brain size , improved neural connectivity , and eased anxiety and social deficits , with benefits persisting into . adulthood This breakthrough highlights lithiumâ s potential to address core ASD mechanisms through its action on Kalirin-7, a molecule critical for synaptic function . The findings underscore the importance of early intervention